Inborn Metabolic Diseases: A Clinical ApproachAbout This Hardback The disease or disorder that disrupts normal metabolism is known as a metabolic disease. It affects the procedure of conversion of food into energy on a cellular level. It also influences the ability of the cell to perform critical biochemical reactions that involve the processing of proteins, carbohydrates and starch. Metabolic diseases are typically hereditary. Some of the symptoms that can occur in metabolic disorders are