Insomnia Treatments: Therapeutic Potential of Orexin AntagonistAbout This Hardback Insomnia or sleeplessness is a sleep disorder which causes difficulty in falling asleep, or staying asleep as long as desired. It also leads to excessive daytime sleepiness, low energy and a depressed mood. Treatment for insomnia usually involves sleep inducing medication, cognitive behavioral therapy for insomnia (CBT i), or a combination of both. Orexins are neurotransmitters in the body that regulate feelings of sleepiness and